Pdgfra-creert2
SpletPericytes are essential mural cells distinguished by their association with small caliber blood vessels and the presence of a basement membrane shared with endothelial cells. … Splet10. apr. 2024 · Aging is associated with a loss of blood stem cell fitness in part due to defects in stem cell-supportive niches. Here, the authors demonstrate that restoring niche function by treatment with ...
Pdgfra-creert2
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Splet07. feb. 2024 · Summary. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens … Splet14. sep. 2016 · In the central nervous system (CNS) platelet derived growth factor receptor alpha (PDGFRα) is expressed exclusively by oligodendrocyte progenitor cells (OPCs), …
Splet06. apr. 2024 · (A) Whole-mount images of SI from Pdgfra CreERT2;R26R mT/mG mice, where Cre-expressing cells convert ubiquitous tdTom fluorescence (red) to eGFP signal (green), counterstained for F-actin (phalloidin, white). 30 μm z stack overlay. The dashed box is enlarged to the right and the crypt in that image is marked with a dashed white line. Splet029684 - Pdgfr-β-CreER [T2] Strain Details. Technical Information Scientists. Overview.
Splet19. mar. 2024 · Pdgfra-CreERT2 mice were a kind gift from Bill Richardson (University College London, London, UK). Fra-2 Tg mice were kindly provided by Erwin Wagner (Research Institute of Molecular Pathology-IMP, Vienna, Austria). We appreciate excellent technical assistance by Thomas Fuchs, Visnja Bubalo, Alexandra Treitler, and Tatjana … SpletFig1. Cre-mediated recombination in the large and small intestine of Pdgfra Cre/+; Rosa26 tdTomato/+ mouse.. Fig2. Cre-mediated recombination in the retina of Pdgfra Cre/+; Rosa26 tdTomato/+ mouse.. Fig3. Detection of tdTomato(red) in various tissues of Pdgfra Cre/+; Rosa26 tdTomato/+ mice. Tdtomato can be detected in the brain, retina, pituitary gland, …
Splet032770 B6.129S- Pdgfra tm1.1(cre/ERT2)Blh /J Pdgfrα-CreER T2 mice have a cre/ERT2 fusion gene inserted into the start codon of the platelet derived growth factor receptor, …
SpletStrain #: 018280. RRID:IMSR_JAX:018280. Pdgfra-creERTM transgenic mice can be used to create conditional mutations in oligodendrocyte precursor or NG2 + cells in the adult … french\u0027s mustard jars historySplet24. maj 2016 · By conditionally knocking out the transcription factor Myelin regulatory factor (Myrf) in OPs, using a tamoxifen-inducible Pdgfra-CreERT2 transgene, we were able to show that blocking production of new oligodendrocytes post-tamoxifen impaired the animals’ ability to learn a motor skill (running on wheels with unevenly spaced rungs), … fasttrack wall panel installationSpletBy using this site, you agree to our Terms and Conditions Got it! french\\u0027s mustard lidSplet23. apr. 2014 · The discovery of stem and progenitor cells in the adult mammalian heart has added a vital dimension to the field of cardiac regeneration. Cardiac-resident stem cells are likely sequestered as reserve cells within myocardial niches during the course of embryonic cardiogenesis, although they may also be recruited from external sources, such as bone … fasttrack wall organization systemSpletNational Center for Biotechnology Information french\u0027s mustard labelSpletA TdTomato-expressing cell (red, arrow) migrates along a vessel (green, outlined by dotted line) at the edge of a 1.5-dpl lesion (Supplementary Video 1). e, Frequency of PDGFRα⁺ OPC clusters at ... fast track wall systemSplet(ii) Confocal image of a Pdgfra–creERT2; R26R–eYFP neonatal long-bone section following cre activation at E9.5, showing eYFP⁺CD45⁺ blood cells in the bone marrow. fasttrack wall rubbermaid