WebSulfonic acids and carboxylic acids are rather electron-withdrawing, but if you drill down into the details of these ipso-substitution reactions, many are actually conducted on the conjugate base ( i.e. sulfonate or carboxylate), which also provides a pathway for loss of a neutral group in the second step, i.e. S O X 3 or C O X 2. WebWebsite. ipso .co .uk. The Independent Press Standards Organisation ( IPSO) is the regulator of the newspaper and magazine industry in the UK. It was established on 8 September 2014 [1] after the windup of the Press Complaints Commission (PCC), which had been the main industry regulator of the press in the United Kingdom since 1990.

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