WebJan 1, 2024 · Récemment, le groupe allemand AIO a rapporté les résultats de l’étude FLOT-4 montrant que l’association d’un sel de platine (l’oxaliplatine), d’une fluoropyrimidine (le 5-fluorouracil en continu sur 24 h) et d’un taxane (le docétaxel) (protocole FLOT), accroissait significativement la survie de patients pris en charge par chimiothérapie péri-opératoire … WebApr 11, 2024 · report the FLOT4 study in The Lancet, which compared perioperative therapy using docetaxel-based triplet FLOT (fluorouracil plus leucovorin, oxaliplatin, and docetaxel) with that using epirubicin and cisplatin plus either fluorouracil or capecitabine (ECF/ECX) in 716 patients with locally advanced gastric or gastro-oesophageal junction …
Perioperative FLOT: new standard for gastric cancer? - The Lancet
WebOct 29, 2024 · Moreover, 5 (15.6%) patients in the ECF group, 10 (19.6%) patients in the DCF group, 1 (2.7%) patient in the FOLFOX group, and 2 (6.3%) patients in the FLOT group experienced anemia as an adverse effect of chemotherapy and the incidence of anemia was not statistically different among treatment regimens (P-value = 0.28). The … WebRésumé et casting HP - Saison 2: Sheila est confrontée à de nouvelles directives administratives absurdes. Pour maintenir à flot le budget de l'HP, seuls les patients les moins lourds sont hospitalisés. early 2000s dickies
Phase II study of perioperative toripalimab in combination with …
WebPatients (pts) with locally advanced, potentially resectable adenocarcinoma of the stomach and GEJ (≥cT2 and/or N-positive) without distant metastases are enrolled. Pts are randomized 1:1 to 4 pre-operative 2-week cycles of FLOT followed by surgery and 4 additional cycles of FLOT + atezolizumab at 840 mg every 2 weeks, followed by a total of ... WebJan 11, 2024 · Salah-Eddin Al-Batran and colleagues1 investigated two perioperative regimens for gastric cancer in the FLOT4 trial. Patients were randomly assigned either to the experimental group receiving fluorouracil plus leucovorin, oxaliplatin, and docetaxel (FLOT) or to the control group receiving epirubicin and cisplatin plus either fluorouracil or … WebMay 25, 2024 · In total, 16 of 20 patients who received FLOT had at least a partial response whereas only 5 of 12 patients who received FOLFOX had any tumor response (p = 0.027). Among all patients receiving neoadjuvant chemotherapy, 66% had poorly differentiated tumors. Only 1 of these patients experiencing a complete or near complete response … early 2000s dating shows