Early endosome antigen 1

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August undefined, 2024

WebEarly endosome antigen 1 (EEA1) is a 170 kDa coiled-coil protein belonging to a group of early endosomal Rab5 effector proteins. EEA1 has a putative role in the tethering/docking of endocytic vesicles prior to their fusion with early endosomes. This protein is characterized as containing a zinc finger-like domain and coiled-coil regions. WebEea1 early endosome antigen 1 [ (house mouse)] Gene ID: 216238, updated on 8-Nov-2024 Summary Predicted to enable 1-phosphatidylinositol binding activity; GTP …

EEA1 - Wikipedia

WebEssential role of Ca2+/calmodulin in Early Endosome Antigen-1 localization. Ca2+ is an essential requirement in membrane fusion, acting through binding proteins such as … WebThe FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization. Lawe DC, Patki V, Heller-Harrison … song with the word love

16783 - Gene ResultLamp1 lysosomal-associated membrane protein 1 …

WebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in segments centered around amino acids 515 and 645. EEA1 contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for N … WebThe gene Early Endosome Antigen 1 (EEA1) encodes for around 1400 amino acid proteins. It is a peripheral membrane protein associated with the cytoplasmic face of early endosomes. EEA1 is a autoantigen associated with subacute cutaneous systemic lupus erythematosus and is a coiled-coil protein localized to early endosomes and cytosol. WebNov 29, 2016 · Early endosome antigen-1 and Ras-related protein-11 expressions were upregulated; however, the localized distributions of these pivotal proteins were altered. We hypothesized that these LVLS were held by the internalized and dispersed particles decreasing the amount of cell membrane available to support the completion of cytokinesis. song with the word refrigerator

Early endosome antigen. 1: An autoantigen associated with …

Monkey Early Endosome Antigen 1 ELISA Kit from …

WebMar 5, 2024 · EEA1 early endosome antigen 1 [Homo sapiens (human)] - Gene - NCBI NCBI Skip to main content Skip to navigation Resources All Resources Chemicals & … WebOct 1, 2013 · Early endosome antigen 1 (EEA1) is a peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence staining of EEA1 in macrophage cells yields punctuate staining pattern consistent with the cytoplasmic distribution of endosomes, but in a different way when compare uninfected-macrophages ( Fig. 2A ) in … small hatchback cars philippinesWebNov 28, 2024 · c Statins counter Mycobacterium tuberculosis-induced phagosome arrest by inducing the expression of early endosome antigen 1 (EEA1), which might be due to increased Ca 2+ levels in macrophages. song with the word party in it

"WebEarly Endosome Antigen 1. In the case of the EEA1 FYVE domain, the emission of a single conserved tryptophan residue located in the head group binding site is quenched … " - Early endosome antigen 1

Early endosome antigen 1

The Emerging Role of Rab5 in Membrane Receptor Trafficking ... - Hindawi

WebDescription: The monoclonal antibody 1G11 recognizes human, mouse and rat early endosome antigen 1 (EEA1). EEA1 is a hydrophilic peripheral membrane protein found in the cytosol and present on early endosome membranes. EEA1 is a dimer that is localized to early endosomes via a cysteine-rich zinc-finger-like FYVE domain. WebJan 17, 2024 · the activation-induced degranulation of Fas ligand has distinct requirements and involves different mechanisms than those of the granule markers CD63 and CD107a/Lamp-1; F. tularensis-containing endosomes associated with early endosome antigen 1 (EEA1) followed by lysosome-associated membrane protein 1 (LAMP-1), with …

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Web3 hours ago · Our studies found that CRB3 could colocalize with EEA1-positive early endosomes, CD63-positive late endosomes and Rab11-positive recycling endosomes . In addition, after 2 hours of ... sequentially. Then, antigen retrieval was performed in Tris-EDTA buffer (pH 9.0) heated to 95°C for 20 min. Endogenous peroxidase activity was … WebJul 10, 2024 · At this stage, ingested materials can be recycled back to the plasma membrane, sent to the trans-Golgi Network (TGN), or degraded through endosomal acidification. Each compartment in the pathway is marked by characteristic proteins, such as early endosome antigen 1 (EEA1), lysosomal-associated membrane protein 1 …

WebEarly endosomes are a major cytoplasmic sorting compartment from which receptors and ligands may be distributed to various sites within the cell. Early endosome antigen 1 (EEA1) is a 180 kDa hydrophilic peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence studies show that EEA1 colocalizes to early … WebAutoantibodies to EEA1, an antigen on early endosomes, were first reported in the serum of a patient with subacute cutaneous lupus erythematosus (SCLE). Here we have …

WebApr 27, 2024 · Therefore, we, co-transfected cells with the well-known tethering protein early endosome antigen 1 (EEA1) tagged to GFP (EEA1-GFP) (Bergeland et al., 2008; … WebMar 3, 2015 · To investigate whether GALNT1 regulates EGFR trafficking, immunofluorescence staining of GALNT1 knockdown HA22T and PLC5 cells treated with EGF 10 ng/ml was performed to analyze for co-localization of EGFR (red) with early endosome antigen 1 (EEA1) (green) or lysosomal associated membrane protein 1 …

WebJul 9, 2024 · The derived amino acid sequence was found to be 99% identical to a 180 kd peripheral endosomal protein named early endosome antigen (EEA1). Results: …

WebItem Monkey Early Endosome Antigen 1 ELISA Kit; Company MyBioSource.com; Price Pricing Info Supplier Page View Company Product Page; Catalog Number MBS051694; Quantity 96 Strip Wells; Applications ELISA; Reactivity Monkey; Detection Target Early Endosome Antigen 1 song with the wordsWebEarly endosomal antigen 1 (EEA1) is a 162 kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations. small hatchbacksWebFeb 1, 2004 · Rab5 together with early endosome antigen 1 (EEA1) 118,119,120 — a phosphoinositide-binding protein — regulate fusion between primary endocytic vesicles and sorting endosomes. More … song with the word silver in the titleWebEEA1 Antibodies. Antibodies that detect EEA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, … song with the word red in itWebEEA1 early endosome antigen 1 [ (human)] Gene ID: 8411, updated on 8-Jan-2024 Summary Enables 1-phosphatidylinositol binding activity; GTP-dependent protein binding … song with the words season of changeWebEarly endosome antigen 1 (EEA1) is an early endosomal protein that contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for … song with the word sleepWebEarly Endosome Antigen 1 Studies of EEA1 have been instrumental in defining the localization of PI(3)P. Closer examination of the protein reveals it is a large coiled-coil protein (Figure 138.3a) that can bind to the GTP-bound form of Rab5, a GTPase required for endosomal membrane fusion [17]. song with the words bang bang