WebMSDS Name: (+)-Camptothecin, 98% Catalog Numbers: AC276720000, AC276721000 Synonyms: Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, … WebSN-38 is an antineoplastic drug. It is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor) but has 1000 times more activity than irinotecan itself. In vitro cytotoxicity assays show that the potency of SN-38 relative to irinotecan varies from 2- to 2000-fold.
Camptothecin, Camptotheca acuminata - Sigma-Aldrich
WebNázev Camptothecin Přístupové číslo DB04690 Popis. Camptothecin je alkaloid izolovaný ze dřeva kmene čínského stromu Camptotheca acuminata. Tato sloučenina selektivně inhibuje jaderný enzym DNA topoizomerázu typu I. Několik polosyntetických analogů kamptothecinu prokázalo protinádorovou aktivitu. WebJul 15, 2024 · SECTION 1: Identification 1.1 GHS Product identifier Product name (S)- (+)-Camptothecin 1.2 Other means of identification 1.3 Recommended use of the chemical … canal boat burgundy
Camptothecin SDS, Safety Data Sheets - ECHEMI
Web(+)-Camptothecin Revision Date 25-Dec-2024 Safety, health and environmental regulations/legislation specific for the substance or mixture Component CAS No OECD … WebCamptothecin and etoposide are inhibitors of nuclear topoisomerase. Cycloheximide, an active antibiotic against many yeast and fungi, inhibits protein synthesis. Dexamethasone, an active and highly stable glucocorticoid, probably induces apoptosis by binding and activating the intracellular glucocorticoid receptor. Supplied with a data sheet. WebCamptothecin (NSC-100880, CPT, Campathecin, (S)- (+)-Camptothecin) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. … canal boat breaks